This is an interesting framed Book Plate which I know nothing about! Sorry, but this is not my area; however, I feel it is worth being treasured by someone who is far more knowledgeable than I. On the lower left hand side below the gentlemen is " I or 1 KAY 1806. On the back of this framed piece someone has pasted a small segment from a page from the book, I assume to be the source of this plate. It talks about Sir James & Mr. Wood and appears to be set in Edinburgh, Scotland. The plate itself measures approximately 5 5/8" x 3 1/2".
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Thank you for looking and Good Luck!