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Organic Chemistry by T. W. Graham Solomons, Craig B. Fr

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Item number:330352079294
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Last updated on 04:44:09 PM PST, Jan 06, 2010 View all revisions
Item specifics - Textbooks, Education
Author: Craig B. Fryhle, T. W. Graham SolomonsFormat: --
Publisher: John Wiley & Sons IncISBN-10: 0471190950
ISBN-13: 9780471190950Educational Level: --
Product Type: --Publication Year: 1999
Subject: Science & TechLanguage: English
Condition: Good  
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Height:10.8 in.
Width:8.3 in.
Thickness:2.0 in.
Weight:91.2 oz.

Publisher's Note
On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100-year-old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It's just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry!

Industry reviews
A textbook that emphasizes the biological, medical, and environmental applications of organic chemistry. Among the changes in this edition (fifth was 1992) are an increased emphasis on reaction mechanisms, some 350 new problems, a revision of the chapter on spectroscopy to include new 300 MHz FT NMR spectra, new and updated material emphasizing biological applications, a new Special Topic on two- dimensional NMR techniques, and the addition of a glossary. Annotation copyright Book News, Inc. Portland, Or.
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Organic Chemistry

T. W. Graham Solomons, Craig B. Fryhle

Book Notes: Organic Chemistry 7TH Edition
Binding: Hardcover
Book Condition: Good
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ISBN: 0471190950
Publication Date: 1999-07
Publisher: John Wiley & Sons
Pages: 1232
Height: 1.8100 inches
Width: 8.0300 inches
Weight: 5.3800 pounds

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